The Ludwig Center at MIT

The Ludwig Center at MIT is focused on the processes associated with malignant progression, specifically on the mechanisms that allow cancer cells originating in primary tumors to disseminate and ultimately form metastatic colonies. This multi-step process involves a series of cell-biological and biochemical changes in malignant cells, which are being investigated at several levels. Our research includes the biological determinants that allow disseminated cancer cells to gain a foothold in foreign tissue microenvironments, where they can succeed in spawning rapidly growing metastatic colonies.